7 Things You Need to Know About Peptides and Polypeptides for Aging Skin

• By Pat Browne
• Sep 10, 2025

Peptides and polypeptides are the unsung heroes of modern skincare, quietly doing the heavy lifting that collagen creams can’t. These amino acid chains signal skin cells to boost collagen, elastin, and hydration while supporting repair, softening wrinkles, and keeping skin firm and luminous. Safe for most skin types — even during pregnancy — they offer a gentler alternative to retinoids with broad anti-aging benefits. And with the rise of epigenetic skincare, peptides are stepping into an even bigger role: helping reprogram skin at the cellular level to act younger and healthier. The result? Resilient, radiant skin that looks as strong as it feels.